U.S – In a recent update, the U.S. Food and Drug Administration (FDA) has outlined its progress and future initiatives in the Cyclospora Prevention, Response, and Research Action Plan. 

The updated action plan includes refined strategies, a report on accomplishments, and three new actions that have been identified by the task force.

This comprehensive strategy, formulated by the FDA’s Cyclospora Task Force in 2021, aims to mitigate the public health impact of foodborne cyclosporiasis in the United States. 

Aligned with the Food Safety Modernization Act (FSMA) and the New Era of Smarter Food Safety, the plan emphasizes preventive measures to combat foodborne illnesses.

The FDA has achieved significant milestones in 2023, demonstrating its commitment to tackling cyclosporiasis. 

One notable accomplishment is the development of a targeted amplicon genotyping assay for C. cayetanensis. This breakthrough assay enhances outbreak and root cause investigations by enabling laboratories to sequence the parasite even when present in low quantities in samples. 

Additionally, the FDA has collaborated with an independent laboratory to create a fully automated screening assay. This innovative technology detects C. cayetanensis in fresh produce, soil, and surface agricultural water, bolstering the agency’s ability to identify contamination sources.

Recognizing the importance of collaboration, the FDA has actively engaged stakeholders through monthly meetings. These discussions serve as a platform for sharing crucial data, promoting food safety research, and fostering a proactive approach to preventing cyclosporiasis. 

The FDA has also provided technical assistance on controlling C. cayetanensis in produce and the environment, underscoring its commitment to supporting research initiatives.

To enhance its testing capabilities, the FDA has expanded its laboratory capacity for detecting C. cayetanensis through the Food Safety Partnership with Mexico. This collaborative effort aims to improve the identification and prevention of cyclosporiasis, benefiting both nations. 

By leveraging expertise from industry, academia, and state and international governments, the FDA’s Cyclospora Task Force aims to close knowledge gaps and make meaningful progress in preventing and reducing cyclosporiasis incidences.

Advancing root cause analyses and research methods

Building upon its achievements, the FDA has outlined three new actions within the Cyclospora Prevention, Response, and Research Action Plan. 

The first action focuses on advancing root cause analyses procedures, ensuring a thorough understanding of the factors contributing to cyclosporiasis outbreaks. 

The second action involves establishing a repository of Cyclospora oocysts, facilitating valuable research opportunities for further insights into the parasite’s characteristics and behavior. 

Lastly, the FDA is dedicated to advancing research methods for conducting comprehensive studies on cyclosporiasis.

The FDA remains committed to providing regular updates on the Cyclospora Action Plan’s progress and key deliverables. 

The updated action plan includes refined strategies, a report on accomplishments, and three new actions that have been identified by the task force.


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By fostering collaboration, prioritizing research, and implementing preventive measures, the FDA aims to protect public health and reduce the burden of foodborne cyclosporiasis in the United States.

The FDA’s proactive approach to combating foodborne illnesses extends beyond cyclosporiasis. 

The agency continues to work towards the goals set forth by the Food Safety Modernization Act (FSMA) and the New Era of Smarter Food Safety, focusing on preventive efforts and leveraging innovative technologies to ensure the safety of the food supply chain. 

By strengthening partnerships and sharing knowledge, the FDA aims to establish a comprehensive framework for safeguarding public health from various foodborne pathogens.

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